American College of Cardiology

First-in-Human Trial Suggests CRISPR-Cas9 Therapy Targeting ANGPTL3 is Safe and Reduces LDL and Triglycerides

A one-time infusion of an investigational CRISPR-Cas9 therapy targeting angiopoietin-like protein 3 (ANGPTL3) was safe and reduced LDL cholesterol by nearly 50% and reduced triglycerides by ...
Science Daily

CRISPR unlocks a new way to defeat resistant lung cancer

Scientists used CRISPR to disable the NRF2 gene, restoring chemotherapy sensitivity in lung cancer cells and slowing tumor growth. The technique worked even when only a fraction of tumor cells were ...
Nature

CRISPR vs cholesterol: can gene editing prevent heart disease?

Promising results from a small clinical trial highlight a growing interest in designing gene-editing treatments for common illnesses. So far, only 15 people have received the treatment. But, if all ...
Reuters

CRISPR gene therapy slashes 'bad' cholesterol, triglycerides by half in small study

CHICAGO, Nov 8 (Reuters) - A single infusion of CRISPR Therapeutics' (CRSP.BN), opens new tab experimental gene therapy was safe and reduced levels of harmful LDL cholesterol and triglycerides by half ...
NPR

CRISPR gene-editing works to reduce high cholesterol in a new study

A single infusion of an experimental gene-editing drug appears safe and effective for cutting cholesterol, possibly for life, according to a small early study released Saturday. The study, which ...