Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...
This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function ...
A Northwestern Medicine study published in the Journal of Clinical Investigation has uncovered a connection between a ...
Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer ...
When MIT neurobiologists tracked how more than 200 motor neurons in fruit flies each edited their RNA, they cataloged hundreds of target sites and widely varying editing rates. Scores of edits altered ...
Spatial RNA medicine combines transcriptomics and RNA therapeutics, mapping gene expression in tissues to enhance precision ...