DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

Zentalis has taken a beating in 2025 to date, as the market continues to value their pipeline as a liability rather than an ...

The field of dermatology has witnessed remarkable progress in the prevention and treatment of skin diseases over the past ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

Researchers found that DNA's shape matters. When its loops break, cancer can start.Based on a new concept of architectural tumor ...

EMBARGOED: A new study to be presented Dec. 6 at the 2025 American Society of Hematology (ASH) meeting reveals that even subtle disruptions in genome architecture can predispose individuals to ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.