DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

Zentalis has taken a beating in 2025 to date, as the market continues to value their pipeline as a liability rather than an ...

The field of dermatology has witnessed remarkable progress in the prevention and treatment of skin diseases over the past ...

Researchers found that DNA's shape matters. When its loops break, cancer can start.Based on a new concept of architectural tumor ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

In a study published in Science Translational Medicine, researchers at Cedars-Sinai report that an experimental drug called TY1 helped damaged hearts heal in laboratory animals. It did not thin blood ...