The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

This article examines some of the cell-based approaches that researchers are using to study acquired drug resistance and the ...

New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in ...

The iSNP systems genomics pipeline models how non-coding SNPs cumulatively impact cellular signalling and gene regulatory networks, revealing patient-specific mechanisms linking disease-associated ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

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