RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

A forested hill and clouds are in the background of an image of a shallow pool of steaming water, with the ground underneath colored in shades of beige, red, and brown. Life may have first emerged in ...

Increased expression of lnc-FANCI-2 in HPV16-infected cervical cancer tissues and HPV16-and HPV18-infected raft culture tissues. (A) Expression lnc-FANCI-2 in HPV16+ cervical cancer tissues were ...

Look inside a brain cell with Huntington’s disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...

Dietitians and doctors have been touting for years the importance of eating a balanced diet to fuel your body properly and lower the risk of chronic diseases such as heart disease and obesity. That ...

Abstract: High-throughput RNA-seq technology has emerged as a powerful tool for understanding the molecular basis of phenotype variation in biology, including disease. Recently, some correlated ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...

1 Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, China 2 Department of Thoracic Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, ...