Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...

The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

TY1 enhances the action of TREX1, a gene that helps immune cells clear damaged DNA, helping to minimize scar tissue post heart attacks.

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune ...