The Colts' loss clinched playoff spots for the Bills and Chargers. The 49ers had already clinched their spot in the NFC, and ...

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats ...

SportsLine's model simulated Indianapolis vs. San Francisco on 'MNF' 10,000 times and reveals its NFL picks today ...

Should DFS managers target Brock Purdy or Philip Rivers on tonight's Monday Night Football DraftKings Showdown slate?

49ers vs Colts final score, results: Brock Purdy throws five touchdowns, 49ers control destiny after win vs. Colts originally ...

Purdy's career night kept the 49ers in the hunt for the NFC's top seed and dampened the Colts' already faint playoff hopes.

A meeting featuring two of the NFL's best in Christian McCaffrey and Jonathan Taylor will close Week 16 as the 49ers and Colts clash in a matchup with playoff implications.

Preview the Week 16 matchup between the San Francisco 49ers and Indianapolis Colts with predictions, odds, over/under, spread, betting lines and more.

The San Francisco 49ers finished their Week 16 "Monday Night Football" contest with a 48-27 win over the Indianapolis Colts at Lucas Oil Stadium.

Break down the 49ers' Week 16 win with PFF grades, snap counts, and top performers—who stood out and who struggled vs. the Colts.

Highlights from the Week 16 matchup between the San Francisco 49ers and the Indianapolis Colts during the 2025 NFL season.

IIIF provides researchers rich metadata and media viewing options for comparison of works across cultural heritage collections. Visit the IIIF page to learn more. The Model 1851 Navy was Colt’s most ...