The 2025 NFL season has entered Week 16, and Sunday's slate promises non-stop action with 12 matchups packed into a marathon ...

Kyle Juszczyk is in line for his 10th Pro Bowl selection after winning the fan vote at fullback. He was the only 49ers player to lead his position. Players are selected on the basis of fan vote, ...

Also inactive for the 49ers were wide receiver Ricky Pearsall Jr., defensive tackle Kevin Givens, running back Isaac Guerendo ...

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats and more for Colts-49ers.

The Lions aren't eliminated just yet. But they can only catch the Packers in the playoff standings, and time and hope is ...

The Indianapolis Colts host the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Live score updates, highlights, where to watch.