A new study shows how one of the cell's most important energy-producing machines is built. Researchers at Karolinska ...
A new study in Nature Communications shows how one of the cell's most important energy-producing machines is built.
Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.
Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, researchers at the University of Basel, Switzerland, have now gained ...
(Top left) Research aim. (Top right) Schema of mitochondrial respiratory chain supercomplex localization and function. (Bottom left) Analysis of supercomplex formation by hrCN-PAGE and in-gel activity ...
Researchers mapped late steps in the formation of the human respirasome, a large protein assembly that drives mitochondrial ...