RNA molecules exhibit an astonishing diversity in structure, which is integral to their myriad cellular functions ranging from gene regulation to catalysis. Advances in experimental techniques and ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function ...

A study captured the first near frame-by-frame view of a self-splicing ribozyme assembling into its active form. Using ...

Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...

A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis ...

Studying a trio of non-coding RNA molecules produced abundantly in bacterial cells, a SLAC/Stanford-led research team discovered extravagant, multistrand complexes made entirely of RNA—structures they ...

Just as AlphaFold2's solution to the protein folding problem heralded a new era in biology and contributed to a Nobel Prize, the accurate prediction of RNA structure is widely considered the next ...

Preclinical in vivo data demonstrate hyper-precise mechanism directly targets the disease-causing mRNA repeats leading to correction of splicing ...

A hidden four-layer structure in the brain’s key memory hub has been revealed, reshaping how scientists understand learning ...

The field of RNA structure prediction and modeling has undergone substantial transformation in recent years, reflecting a confluence of innovative computational strategies and expanding experimental ...

Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease and Stephen Hawking’s disease, is a neurodegenerative disease that results in the gradual loss of control over the muscles ...