This is a preview. Log in through your library . Abstract Long-term potentiation (LTP) is a cellular mechanism of learning and memory that results in a sustained increase in the probability of ...
α-Synuclein (α-Syn) is a presynaptic protein primarily associated with Parkinson’s disease and other neurodegenerative diseases. The cholesterol content in SV membranes regulates α-Syn binding to ...
Our model proposes that in synapses, ATM protein localizes predominately in presynaptic terminals, while ATR localizes on both side of synapse. ATM binds exclusively to VGLUT1+ vesicles, while ATR ...
The synaptotagmin protein family has been studied by neuroscientists for decades. However, most isoforms lack well-defined functions. Now, researchers have identified a crucial, presynaptic role for ...
Phosphorylation of α-synuclein at serine 129 has long been used as a marker of synucleinopathy—p-S129syn accumulates in Lewy bodies, after all. But does this modification have a physiological function ...
α-synuclein (α-syn) is a small presynaptic protein linked to the pathogenesis of Parkinson’s disease (PD) and related disorders, collectively called synucleinopathies. Phosphorylation of α-syn at ...
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