As the importance and prevalence of oligonucleotide therapeutics continue to grow, so does the need for robust characterization methodologies throughout drug development and production. Given the ...

Fluorinated compounds are increasingly used in medicinal, agricultural, and material science applications. NMR probes and procedures were historically employed to get hydrogen and carbon spectra.

Fragment-based drug discovery (FBDD) has emerged as a transformative approach in medicinal chemistry by focusing on the identification of small chemical fragments that bind to biologically relevant ...

Nuclear magnetic resonance (NMR) is an information-rich technique. However, it requires a higher analyte concentration than all other spectroscopic methods, especially when compared to analytical ...

Confluence of Major NMR Methods and Instrumentation Advances Enables Next-Generation GHz Technology with Focus on Structural Biology, Macromolecular Complexes, Membrane Proteins and Intrinsically ...

NMR (Nuclear Magnetic Resonance) spectroscopy is a powerful analytical technique that provides detailed information about the structure, dynamics, and chemical environment of molecules at the atomic ...

Zeolites are widely used in many industries. There is still a need to fully understand their intrinsic catalytic nature due to the complexity of the hydroxyl-aluminum moieties. Atomic-scale analysis ...

With the publication of ICH Q2(R2) and ICH Q14, the modern Quality by Design (QbD) paradigm introduced by ICH Q8 for manufacturing has now been extended to Quality Control (QC). A life cycle and ...

Researchers have achieved a breakthrough in zero-field nuclear magnetic resonance spectroscopy, paving the way towards benchmarking quantum chemistry calculations. What is the structure of a ...