This is a preview. Log in through your library . Abstract Two subfragments of laminin, E8, a major part of the long arm, and E1-4, the three short arms, promote cell adhesion and spreading. Three ...

Like a plug and a socket, a nerve and a muscle fiber mesh at the neuromuscular junction. New work reveals that an extracellular matrix protein called laminin shapes both sides of the junction to ...

Laminin-332 is major component of epithelial basement membrane, and has an important role in cell migration and tumour invasion. Recently, the phosphatidylinositol 3-kinase (PI3K) activation induced ...

Researchers have shown how the protein laminin, long thought to provide only structural support in the microenvironment of breast and other epithelial tissue, can play a leading role in the ...

The laminin-411 protein is vital for the formation of the myelin membrane by oligodendrocytes, report researchers from Japan. Furthermore, the A4G47 peptide from the E8 region of laminin-411 was found ...

Nucleosomes—key autoantigens involved in the pathogenesis of lupus nephritis (LN)—bind to aberrantly expressed laminin-β1 and localize to electron-dense deposits (EDDs) within the glomerular basement ...

Our understanding of the mechanisms by which ducts and lobules develop is derived from model organisms and three-dimensional (3D) cell culture models wherein mammalian epithelial cells undergo ...

Laminin, long thought to be only a structural support protein in the microenvironment of breast and other epithelial tissues, is "famous" for its cross-like shape. However, laminin is far more than ...

Cells are capable of translating mechanical changes into biological responses. This process is known as mechanotransduction and plays a fundamental role in the progression of solid tumors, such as ...

Combined irinotecan and cisplatin therapy for extrapulmonary small cell carcinoma (EPSCC). This is an ASCO Meeting Abstract from the 2011 ASCO Annual Meeting I. This abstract does not include a full ...

Scientists at the University of Osaka have developed a novel hydrogel that enables the efficient, three-dimensional (3D) culture of human induced pluripotent stem cells (iPSCs). Subscribe to our ...

Like a plug and a socket, a nerve and a muscle fiber mesh at the neuromuscular junction. New work by Nishimune et al published in the Journal of Cell Biology reveals that an extracellular matrix ...