Acquired Factor V inhibitors represent a rare and heterogeneous group of coagulation disorders, characterised by the sudden emergence of autoantibodies that neutralise factor V, a critical cofactor in ...

DEAR DR ROACH: I have Factor V Leiden, but I have been wanting to do testosterone replacement therapy. I have heard that testosterone causes blood clots. Obviously, with FVL, that would be a huge deal ...

The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Isolated Factor V deficiency is a very rare inherited coagulopathy. A genealogy of Brazilian Caucasians, where this disorder occurs, is reported. In this family, which was located because 2 affected ...

Genetic research in Sweden has unveiled three new gene variants that dramatically increase the risk of venous blood clots, sometimes by up to 180%. These discoveries build on existing knowledge of ...

DEAR DR. ROACH: My son was recently diagnosed with factor V Leiden. He has had heart issues since he was 12 (chest pain, irregular EKGs with no explanation and intermittent irregular heart rate). He ...