A major new initiative involving Leicester experts aims to redefine human-based research models for greater understanding of disease and the acceleration of new medicines ...

Scientists have created a bioengineered 3-D model that mimics the biology of two rare diseases. The researchers used the 'tissue chip' model to show how a drug could potentially treat the diseases, ...

Many statistical models and algorithms used by scientists can be imagined as a "black box." These models are powerful tools that give accurate predictions, but their internal workings are not easily ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...