Six feet of DNA crammed into a cell nucleus narrower than a human hair: ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

Understanding the dynamic behavior of DNA remains an important challenge to biophysics, in particular the folding and stretching of DNA is critical since protein-DNA interactions require that the ...

A cell has many ways to regulate gene expression, one of which is the structure of the genome itself; active genes have to be accessible to the cellular machinery to be expressed. The DNA in the ...

The discovery of DNA-binding proteins could provide a new target for development of drugs to prevent or treat bacterial infection. Scientists have revealed for the first time the molecular steps that ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

The double helix of DNA is one of the most iconic symbols in science. By imitating the structure of this complex genetic molecule we have found a way to make artificial muscle fibers far more powerful ...

Scientists at the Department of Energy's Lawrence Berkeley National Laboratory have elucidated the process that activates the pathogenic genes of a bacterium. Publishing in Science Adavances, the ...