CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily ...

Drug resistance has long turned some of the most advanced lung cancer therapies into temporary victories, with tumors learning to shrug off chemotherapy that once held them in check. A new wave of ...

CRISPR is a gene-editing tool that acts like “molecular scissors,” but using it on cancer is complex. The technology’s biggest impact so far is in research labs, helping scientists understand how ...

In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in ...

The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive and difficult-to-treat brain cancer known as primary glioblastoma, according to new findings. The ...

A Mount Sinai team showed that the same leukemia mutation behaves differently depending on when it arises during development.

Researchers used CRISPR screening in tumor organoids and mice to identify two genes, Ctnna1 and Bcl2l13, that suppress ...

Breast cancer (BC) remains the most prevalent cancer among women worldwide, presenting significant challenges due to its high incidence and mortality rates. Traditional treatments, such as ...

The immune system plays a crucial role in fighting tumors and metastases. Consequently, it is decisive to conduct cancer research in mouse models with an immune system that is as natural as possible – ...

A study led by University of Cincinnati Cancer Center researchers sheds new light on how pancreatic cancer cells resist treatment and points to potential new combination therapies to make treatments ...

New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in ...