E. A. Espiner, M.D., M.R.A.C.P., P. I. Jagger, M.D., J. R. Tucci, M.D., and D. P. Lauler, M.D. In nine separate studies on four patients with severe pitting edema ...

Primary aldosteronism management depends on a multitude of factors, and surgical adrenalectomy is generally recommended in ...

A drug that has been used to slow progression of kidney and cardiovascular disease in people with type 2 diabetes may also help people with chronic kidney disease who do not have diabetes, according ...

Higher serum aldosterone levels among patients with chronic kidney disease (CKD) are independently associated with an increased risk for CKD progression and end-stage kidney disease (ESKD) regardless ...

Please provide your email address to receive an email when new articles are posted on . Dysregulated aldosterone production, sometimes driven by obesity, can cause hypertension. Targeted therapies ...

In a phase 2 trial, an investigational drug that inhibits aldosterone synthase significantly lowered albuminuria in patients with or without type 2 diabetes. PHILADELPHIA—A novel selective aldosterone ...

Laragh also played a pivotal part in elucidating the role of aldosterone in the pathogenesis of malignant hypertension and CV disease in general. [10,11] He was an outstanding clinician-scientist who ...

The coronavirus disease 2019 (COVID-19) pandemic caused millions of deaths throughout the world, which has provoked intense research into the pathogenetic mechanism behind this disease. A new study ...

(HealthDay News) — For patients with hypertension and obstructive sleep apnea (OSA), treatment with losartan does not lead to significant reductions in aldosterone, but the treatment is tied to ...

PHILADELPHIA -- An oral investigational aldosterone synthase inhibitor (ASI) cut albuminuria by nearly 40% in people in chronic kidney disease (CKD) in a phase II trial. The 10-mg dose of ASI BI ...